SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.905037 View
ENSG00000132694 ARHGEF11 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.905015 View
ENSG00000141646 SMAD4 ENSG00000167815 PRDX2 H. sapiens SSL Slorth 0.90499 View
ENSG00000139719 VPS33A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.904937 View
ENSG00000134686 PHC2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.904871 View
ENSG00000141646 SMAD4 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.90452 View
ENSG00000141646 SMAD4 ENSG00000161270 NPHS1 H. sapiens SDL Slorth 0.904426 View
ENSG00000125952 MAX ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.904304 View
ENSG00000101412 E2F1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.904142 View
ENSG00000066468 FGFR2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.903879 View
ENSG00000141646 SMAD4 ENSG00000155511 GRIA1 H. sapiens SDL Slorth 0.903847 View
ENSG00000122566 HNRNPA2B1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903808 View
ENSG00000114737 CISH ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.9038 View
ENSG00000127445 PIN1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903782 View
ENSG00000141646 SMAD4 ENSG00000175390 EIF3F H. sapiens SDL Slorth 0.903773 View
ENSG00000141646 SMAD4 ENSG00000213024 NUP62 H. sapiens SDL Slorth 0.903769 View
ENSG00000105329 TGFB1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903618 View
ENSG00000101310 SEC23B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903525 View
ENSG00000096717 SIRT1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903418 View
ENSG00000141646 SMAD4 ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.903275 View
ENSG00000141646 SMAD4 ENSG00000145349 CAMK2D H. sapiens SSL Slorth 0.903262 View
ENSG00000111424 VDR ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.903199 View
ENSG00000116266 STXBP3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.90316 View
ENSG00000092010 PSME1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.903027 View
ENSG00000121989 ACVR2A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.902951 View
ENSG00000141646 SMAD4 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.902857 View
ENSG00000141646 SMAD4 ENSG00000149269 PAK1 H. sapiens SSL Slorth 0.902698 View
ENSG00000127481 UBR4 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.902602 View
ENSG00000141646 SMAD4 ENSG00000143507 DUSP10 H. sapiens SSL Slorth 0.902446 View
ENSG00000125885 MCM8 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.902384 View
ENSG00000070756 PABPC1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.90238 View
ENSG00000141646 SMAD4 ENSG00000166333 ILK H. sapiens SSL Slorth 0.902297 View
ENSG00000141646 SMAD4 ENSG00000213585 VDAC1 H. sapiens SSL Slorth 0.902079 View
ENSG00000141646 SMAD4 ENSG00000198900 TOP1 H. sapiens SDL Slorth 0.902072 View
ENSG00000141646 SMAD4 ENSG00000166167 BTRC H. sapiens SSL Slorth 0.901995 View
ENSG00000111859 NEDD9 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.901975 View
ENSG00000089157 RPLP0 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.901959 View
ENSG00000123374 CDK2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.901911 View
ENSG00000106588 PSMA2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.901827 View
ENSG00000141646 SMAD4 ENSG00000167216 KATNAL2 H. sapiens SDL Slorth 0.901799 View