POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000138032 PPM1B H. sapiens SSL Slorth 0.92774 View
ENSG00000101868 POLA1 ENSG00000126777 KTN1 H. sapiens SSL Slorth 0.927719 View
ENSG00000101868 POLA1 ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.927626 View
ENSG00000101868 POLA1 ENSG00000144852 NR1I2 H. sapiens SSL Slorth 0.927614 View
ENSG00000101868 POLA1 ENSG00000129219 PLD2 H. sapiens SSL Slorth 0.92747 View
ENSG00000101868 POLA1 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.927313 View
ENSG00000101868 POLA1 ENSG00000108061 SHOC2 H. sapiens SSL Slorth 0.92731 View
ENSG00000101868 POLA1 ENSG00000131462 TUBG1 H. sapiens SSL Slorth 0.927156 View
ENSG00000101868 POLA1 ENSG00000113595 TRIM23 H. sapiens SSL Slorth 0.927103 View
ENSG00000101003 GINS1 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.927091 View
ENSG00000101868 POLA1 ENSG00000135486 HNRNPA1 H. sapiens SDL Slorth 0.927026 View
ENSG00000101868 POLA1 ENSG00000221823 PPP3R1 H. sapiens SSL Slorth 0.926984 View
ENSG00000101868 POLA1 ENSG00000137267 TUBB2A H. sapiens SSL Slorth 0.92697 View
ENSG00000101868 POLA1 ENSG00000117650 NEK2 H. sapiens SSL Slorth 0.926923 View
ENSG00000101868 POLA1 ENSG00000138107 ACTR1A H. sapiens SSL Slorth 0.926878 View
ENSG00000101868 POLA1 ENSG00000197451 HNRNPAB H. sapiens SSL Slorth 0.926791 View
ENSG00000101868 POLA1 ENSG00000105063 PPP6R1 H. sapiens SSL Slorth 0.926749 View
ENSG00000101868 POLA1 ENSG00000128059 PPAT H. sapiens SSL Slorth 0.926747 View
ENSG00000101868 POLA1 ENSG00000166803 KIAA0101 H. sapiens SSL Slorth 0.92672 View
ENSG00000101868 POLA1 ENSG00000109971 HSPA8 H. sapiens SDL Slorth 0.92643 View
ENSG00000101868 POLA1 ENSG00000135597 REPS1 H. sapiens SDL Slorth 0.926373 View
ENSG00000101868 POLA1 ENSG00000105397 TYK2 H. sapiens SSL Slorth 0.926345 View
ENSG00000010810 FYN ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.926059 View
ENSG00000101868 POLA1 ENSG00000125257 ABCC4 H. sapiens SSL Slorth 0.925989 View
ENSG00000101868 POLA1 ENSG00000138160 KIF11 H. sapiens SSL Slorth 0.925883 View
ENSG00000101868 POLA1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.925641 View
ENSG00000101868 POLA1 ENSG00000124795 DEK H. sapiens SSL Slorth 0.92563 View
ENSG00000101868 POLA1 ENSG00000148308 GTF3C5 H. sapiens SSL Slorth 0.925602 View
ENSG00000101868 POLA1 ENSG00000171456 ASXL1 H. sapiens SSL Slorth 0.925567 View
ENSG00000077721 UBE2A ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.925547 View
ENSG00000101868 POLA1 ENSG00000104517 UBR5 H. sapiens SDL Slorth 0.925453 View
ENSG00000101868 POLA1 ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.925314 View
ENSG00000101868 POLA1 ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.925314 View
ENSG00000101868 POLA1 ENSG00000165410 CFL2 H. sapiens SSL Slorth 0.925306 View
ENSG00000101868 POLA1 ENSG00000157823 AP3S2 H. sapiens SSL Slorth 0.925259 View
ENSG00000101868 POLA1 ENSG00000186153 WWOX H. sapiens SSL Slorth 0.925213 View
ENSG00000101868 POLA1 ENSG00000105220 GPI H. sapiens SSL Slorth 0.925131 View
ENSG00000101868 POLA1 ENSG00000141580 WDR45B H. sapiens SSL Slorth 0.925102 View
ENSG00000101868 POLA1 ENSG00000215114 UBXN2B H. sapiens SSL Slorth 0.925099 View
ENSG00000101868 POLA1 ENSG00000144118 RALB H. sapiens SSL Slorth 0.925094 View