CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000169083 AR H. sapiens SDL Slorth 0.972022 View
ENSG00000089159 PXN ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971997 View
ENSG00000080815 PSEN1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971968 View
ENSG00000100644 HIF1A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.971888 View
ENSG00000135018 UBQLN1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971803 View
ENSG00000135446 CDK4 ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.97179 View
ENSG00000111276 CDKN1B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971756 View
ENSG00000135446 CDK4 ENSG00000143420 ENSA H. sapiens SDL Slorth 0.971746 View
ENSG00000135446 CDK4 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.971709 View
ENSG00000123374 CDK2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.97163 View
ENSG00000135446 CDK4 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.971611 View
ENSG00000135446 CDK4 ENSG00000176720 BOK H. sapiens SDL Slorth 0.971554 View
ENSG00000104365 IKBKB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971301 View
ENSG00000135446 CDK4 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.971247 View
ENSG00000135446 CDK4 ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.971245 View
ENSG00000135446 CDK4 ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.971223 View
ENSG00000117399 CDC20 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971157 View
ENSG00000114166 KAT2B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.971143 View
ENSG00000135446 CDK4 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.971116 View
ENSG00000135446 CDK4 ENSG00000162434 JAK1 H. sapiens SSL Slorth 0.971091 View
ENSG00000135446 CDK4 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.971063 View
ENSG00000100030 MAPK1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.97102 View
ENSG00000110395 CBL ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.97098 View
ENSG00000135446 CDK4 ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.970926 View
ENSG00000135446 CDK4 ENSG00000139343 SNRPF H. sapiens SSL Slorth 0.970712 View
ENSG00000135446 CDK4 ENSG00000166167 BTRC H. sapiens SSL Slorth 0.970563 View
ENSG00000135446 CDK4 ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.970547 View
ENSG00000135446 CDK4 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.970517 View
ENSG00000135446 CDK4 ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.9704 View
ENSG00000135446 CDK4 ENSG00000137825 ITPKA H. sapiens SDL Slorth 0.970319 View
ENSG00000119048 UBE2B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.970167 View
ENSG00000135446 CDK4 ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.970129 View
ENSG00000109971 HSPA8 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.970095 View
ENSG00000101146 RAE1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.969953 View
ENSG00000135446 CDK4 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.969942 View
ENSG00000082701 GSK3B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.969893 View
ENSG00000135446 CDK4 ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.969883 View
ENSG00000135446 CDK4 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.969853 View
ENSG00000135446 CDK4 ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.96969 View
ENSG00000135446 CDK4 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.969543 View