ITK

ENSG00000113263 - H. sapiens

Pathways

Go term Description
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0005102 receptor binding

Drugs

Drug name Description
PAZOPANIB Tyrosine-protein kinase LCK inhibitor

Diseases

Disease Name
peripheral T-cell lymphoma

Orthologs

Gene Organism
Btk29A D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000103035 PSMD7 ENSG00000113263 ITK H. sapiens SDL Slorth 0.937161 View
ENSG00000113263 ITK ENSG00000186868 MAPT H. sapiens SDL Slorth 0.93665 View
ENSG00000026103 FAS ENSG00000113263 ITK H. sapiens SDL Slorth 0.935565 View
ENSG00000101266 CSNK2A1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.934755 View
ENSG00000010810 FYN ENSG00000113263 ITK H. sapiens SSL Slorth 0.932642 View
ENSG00000041357 PSMA4 ENSG00000113263 ITK H. sapiens SDL Slorth 0.932115 View
ENSG00000113263 ITK ENSG00000165025 SYK H. sapiens SDL Slorth 0.929299 View
ENSG00000113263 ITK ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.929001 View
ENSG00000113263 ITK ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.927815 View
ENSG00000100030 MAPK1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.927201 View
ENSG00000096384 HSP90AB1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.92672 View
ENSG00000113263 ITK ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.922002 View
ENSG00000113263 ITK ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.92093 View
ENSG00000106588 PSMA2 ENSG00000113263 ITK H. sapiens SDL Slorth 0.920434 View
ENSG00000111276 CDKN1B ENSG00000113263 ITK H. sapiens SDL Slorth 0.916225 View
ENSG00000004700 RECQL ENSG00000113263 ITK H. sapiens SSL Slorth 0.915044 View
ENSG00000103275 UBE2I ENSG00000113263 ITK H. sapiens SSL Slorth 0.914733 View
ENSG00000084774 CAD ENSG00000113263 ITK H. sapiens SDL Slorth 0.914117 View
ENSG00000113263 ITK ENSG00000162434 JAK1 H. sapiens SDL Slorth 0.913193 View
ENSG00000055130 CUL1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.913109 View
ENSG00000112306 RPS12 ENSG00000113263 ITK H. sapiens SDL Slorth 0.911118 View
ENSG00000008018 PSMB1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.910479 View
ENSG00000100519 PSMC6 ENSG00000113263 ITK H. sapiens SDL Slorth 0.909113 View
ENSG00000005339 CREBBP ENSG00000113263 ITK H. sapiens SSL Slorth 0.906749 View
ENSG00000113263 ITK ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.901926 View
ENSG00000113263 ITK ENSG00000113721 PDGFRB H. sapiens SDL Slorth 0.90164 View
ENSG00000101336 HCK ENSG00000113263 ITK H. sapiens SDL Slorth 0.901442 View
ENSG00000113263 ITK ENSG00000115904 SOS1 H. sapiens SDL Slorth 0.901335 View
ENSG00000113263 ITK ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.900681 View
ENSG00000110395 CBL ENSG00000113263 ITK H. sapiens SSL Slorth 0.89754 View
ENSG00000012048 BRCA1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.896122 View
ENSG00000113263 ITK ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.892724 View
ENSG00000113263 ITK ENSG00000283094 PTEN H. sapiens SSL Slorth 0.891624 View
ENSG00000082701 GSK3B ENSG00000113263 ITK H. sapiens SSL Slorth 0.890981 View
ENSG00000113263 ITK ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.889314 View
ENSG00000113263 ITK ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.889152 View
ENSG00000101868 POLA1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.88913 View
ENSG00000072401 UBE2D1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.888502 View
ENSG00000049759 NEDD4L ENSG00000113263 ITK H. sapiens SSL Slorth 0.888007 View
ENSG00000108443 RPS6KB1 ENSG00000113263 ITK H. sapiens SSL Slorth 0.885773 View