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Slorth
PDGFRA - LCK
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PDGFRA
ENSG00000134853
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma
BECAPLERMIN
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
SUNITINIB
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
vascular endothelial growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
platelet-derived growth factor receptor binding
protein binding
ATP binding
vascular endothelial growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
LCK
ENSG00000182866
T-ALL
DASATINIB
PAZOPANIB
glycoprotein binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
protein kinase binding
protein phosphatase binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
ATPase binding
Src64B (D. melanogaster)