POLD1 - FLT3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
FLT3	ENSG00000122025	AML ALL	CABOZANTINIB SORAFENIB SUNITINIB	transmembrane receptor protein tyrosine kinase activity cytokine receptor activity vascular endothelial growth factor-activated receptor activity protein binding ATP binding protein complex binding glucocorticoid receptor binding protein homodimerization activity	Pvr (D. melanogaster)