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KMT2A - TOP1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
KMT2A
ENSG00000118058
AML
ALL
No drugs in record
core promoter sequence-specific DNA binding
AT DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
identical protein binding
protein homodimerization activity
transcription regulatory region DNA binding
unmethylated CpG binding
lysine-acetylated histone binding
SET1 (S. cerevisiae)
trx (D. melanogaster)
TOP1
ENSG00000198900
AML*
IRINOTECAN
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
protein binding
isomerase activity
DNA topoisomerase activity
TOP1 (S. cerevisiae)
top-1 (C. elegans)
Top1 (D. melanogaster)