KMT2A - PTEN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KMT2A	ENSG00000118058	AML ALL	No drugs in record	core promoter sequence-specific DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding zinc ion binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K4 specific) identical protein binding protein homodimerization activity transcription regulatory region DNA binding unmethylated CpG binding lysine-acetylated histone binding	SET1 (S. cerevisiae) trx (D. melanogaster)
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)