PDGFRB - EPS8L2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PDGFRB ENSG00000113721 MPN
AML
CMML
CML
BECAPLERMIN
DASATINIB
IMATINIB
NINTEDANIB
PAZOPANIB
REGORAFENIB
SORAFENIB
SUNITINIB
protein tyrosine kinase activity
platelet activating factor receptor activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
enzyme binding
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
EPS8L2 ENSG00000177106

No diseases in record

No drugs in record

actin binding
cadherin binding involved in cell-cell adhesion
Rho guanyl-nucleotide exchange factor activity
Rac guanyl-nucleotide exchange factor activity
eps-8 (C. elegans)
aru (D. melanogaster)
CG8907 (D. melanogaster)