PDGFRB - ACTN4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
ACTN4	ENSG00000130402	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding nucleoside binding actin binding integrin binding calcium ion binding protein binding ligand-dependent nuclear receptor transcription coactivator activity chromatin DNA binding nuclear hormone receptor binding protein homodimerization activity retinoic acid receptor binding ion channel binding protein N-terminus binding actin filament binding	atn-1 (C. elegans) Actn (D. melanogaster)