PDGFRB - ITPR1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
ITPR1	ENSG00000150995	No diseases in record	No drugs in record	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium ion binding protein binding calcium ion transmembrane transporter activity calcium-release channel activity calcium channel inhibitor activity phosphatidylinositol binding inositol 1,4,5 trisphosphate binding	itr-1 (C. elegans)