KIT - KALRN

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
KIT ENSG00000157404 GIST
AML
TGCT
mastocytosis
mucosal melanoma
epithelioma
CABOZANTINIB
DASATINIB
IMATINIB
LENVATINIB
PAZOPANIB
PONATINIB
REGORAFENIB
SORAFENIB
SUNITINIB
protease binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
stem cell factor receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
cytokine binding
protein homodimerization activity
metal ion binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Pvr (D. melanogaster)
KALRN ENSG00000160145

No diseases in record

No drugs in record

protein serine/threonine kinase activity
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
ATP binding
Rac guanyl-nucleotide exchange factor activity
metal ion binding
unc-73 (C. elegans)
trio (D. melanogaster)