BIRC2 - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BIRC2	ENSG00000110330	No diseases in record	No drugs in record	transcription coactivator activity ubiquitin-protein transferase activity protein binding zinc ion binding transferase activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process ubiquitin binding protein N-terminus binding chaperone binding FBXO family protein binding	Diap2 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)