ARRB2 - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARRB2	ENSG00000141480	No diseases in record	No drugs in record	G-protein coupled receptor binding receptor binding protein binding enzyme binding protein domain specific binding ubiquitin protein ligase binding alpha-1A adrenergic receptor binding alpha-1B adrenergic receptor binding angiotensin receptor binding type 1 angiotensin receptor binding D1 dopamine receptor binding follicle-stimulating hormone receptor binding type 2A serotonin receptor binding platelet activating factor receptor binding protein complex binding protein complex scaffold activity protein kinase B binding mitogen-activated protein kinase binding 14-3-3 protein binding	Arr1 (D. melanogaster) krz (D. melanogaster) Arr2 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)