PRKCZ - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRKCZ	ENSG00000067606	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein kinase C activity protein binding ATP binding potassium channel regulator activity protein kinase binding protein domain specific binding phospholipase binding insulin receptor substrate binding metal ion binding 14-3-3 protein binding	PKC1 (S. cerevisiae) aPKC (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)