MAPK3 - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAPK3	ENSG00000102882	No diseases in record	No drugs in record	phosphotyrosine residue binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding kinase activity phosphatase binding scaffold protein binding	FUS3 (S. cerevisiae) KSS1 (S. cerevisiae) mpk-1 (C. elegans) rl (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)