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CASP8 - HDAC1
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
CASP8
ENSG00000064012
hepatocellular
oral squamous cell
breast
No drugs in record
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
cysteine-type peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
identical protein binding
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Dredd (D. melanogaster)
HDAC1
ENSG00000116478
No diseases in record
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
transcription regulatory region sequence-specific DNA binding
core promoter binding
RNA polymerase II transcription factor binding
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
activating transcription factor binding
histone deacetylase binding
transcription regulatory region DNA binding
protein N-terminus binding
NF-kappaB binding
repressing transcription factor binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
RPD3 (S. cerevisiae)
hda-1 (C. elegans)
hda-3 (C. elegans)