YWHAH - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
YWHAH	ENSG00000128245	No diseases in record	No drugs in record	actin binding insulin-like growth factor receptor binding protein binding sodium channel regulator activity enzyme binding protein domain specific binding glucocorticoid receptor binding ion channel binding protein heterodimerization activity	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) par-5 (C. elegans) ftt-2 (C. elegans) 14-3-3zeta (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)