KDR - PPM1D

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)
PPM1D	ENSG00000170836	glioma ovarian cancer breast cancer	No drugs in record	protein serine/threonine phosphatase activity protein binding metal ion binding mitogen-activated protein kinase binding	PTC2 (S. cerevisiae) PTC3 (S. cerevisiae)