CDK6 - KDR

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
CDK6 ENSG00000105810 ALL
PALBOCICLIB
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
cyclin binding
FBXO family protein binding
CDC28 (S. cerevisiae)
cdk-4 (C. elegans)
Cdk4 (D. melanogaster)
KDR ENSG00000128052 NSCLC
angiosarcoma
melanoma
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
Pvr (D. melanogaster)