ESR1 - MAP2K2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ESR1 ENSG00000091831 breast
BAZEDOXIFENE
DIENESTROL
DIETHYLSTILBESTROL
DIETHYLSTILBESTROL DIPHOSPHATE
ENCLOMIPHENE
ESTRADIOL
ESTRADIOL ACETATE
ESTRADIOL CYPIONATE
ESTRADIOL VALERATE
ESTROGENS, CONJUGATED
ESTROGENS, CONJUGATED SYNTHETIC A
ESTROGENS, ESTERIFIED
ESTRONE
ESTRONE SULFURIC ACID
ETHINYL ESTRADIOL
FULVESTRANT
MESTRANOL
OSPEMIFENE
POLYESTRADIOL PHOSPHATE
QUINESTROL
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B
TAMOXIFEN
TOREMIFENE
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
steroid binding
protein binding
beta-catenin binding
transcription factor binding
zinc ion binding
enzyme binding
nitric-oxide synthase regulator activity
estrogen receptor activity
estrogen response element binding
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
identical protein binding
ATPase binding

No GO terms in record

MAP2K2 ENSG00000126934 NSCLC
melanoma
TRAMETINIB
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
PDZ domain binding
protein serine/threonine kinase activator activity
metal ion binding
scaffold protein binding
PBS2 (S. cerevisiae)
mek-2 (C. elegans)
Dsor1 (D. melanogaster)