UBE2I - BRAF

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBE2I	ENSG00000103275	No diseases in record	No drugs in record	protein binding ATP binding transcription factor binding ligase activity SUMO transferase activity enzyme binding HLH domain binding SUMO conjugating enzyme activity RING-like zinc finger domain binding ubiquitin protein ligase binding ubiquitin protein ligase activity	UBC9 (S. cerevisiae) lwr (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)