PDGFRB - ERCC5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
ERCC5	ENSG00000134899	skin basal cell skin squamous cell melanoma	No drugs in record	bubble DNA binding double-stranded DNA binding single-stranded DNA binding endodeoxyribonuclease activity protein binding protein homodimerization activity metal ion binding protein N-terminus binding	RAD2 (S. cerevisiae) xpg-1 (C. elegans)