KDR - TAL1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)
TAL1	ENSG00000162367	lymphoblastic leukaemia/biphasic	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding enzyme binding histone deacetylase binding transcription regulatory region DNA binding protein heterodimerization activity E-box binding sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity transferase activity catalytic activity	HLH3B (D. melanogaster)