MLH1 - KDR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MLH1	ENSG00000076242	colorectal endometrial ovarian CNS tumours CNS	No drugs in record	chromatin binding protein binding ATP binding ATPase activity guanine/thymine mispair binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding DNA binding	MLH1 (S. cerevisiae) Mlh1 (D. melanogaster)
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)