PDGFRB - SMG1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PDGFRB ENSG00000113721 MPN
AML
CMML
CML
BECAPLERMIN
DASATINIB
IMATINIB
NINTEDANIB
PAZOPANIB
REGORAFENIB
SORAFENIB
SUNITINIB
protein tyrosine kinase activity
platelet activating factor receptor activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
enzyme binding
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
SMG1 ENSG00000157106

No diseases in record

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
telomeric DNA binding
metal ion binding
molecular_function
TOR1 (S. cerevisiae)
smg-1 (C. elegans)
nonC (D. melanogaster)