MAP2K4 - PDGFRB

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K4	ENSG00000065559	pancreatic breast colorectal	No drugs in record	protein kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding JUN kinase kinase activity mitogen-activated protein kinase kinase kinase binding	PBS2 (S. cerevisiae) sek-3 (C. elegans) mkk-4 (C. elegans) sek-6 (C. elegans) Mkk4 (D. melanogaster)
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)