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ARFGEF1 - KDR
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
ARFGEF1
ENSG00000066777
No diseases in record
No drugs in record
guanyl-nucleotide exchange factor activity
ARF guanyl-nucleotide exchange factor activity
protein binding
myosin binding
protein kinase A regulatory subunit binding
GTPase activator activity
SEC7 (S. cerevisiae)
Sec71 (D. melanogaster)
KDR
ENSG00000128052
NSCLC
angiosarcoma
melanoma
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
Pvr (D. melanogaster)