PIAS1 - KDR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS1	ENSG00000033800	No diseases in record	No drugs in record	DNA binding transcription coactivator activity transcription corepressor activity protein binding protein C-terminus binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity enzyme binding protein domain specific binding ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)