KDR - TAF1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)
TAF1	ENSG00000147133	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly p53 binding transcription coactivator activity histone acetyltransferase activity protein serine/threonine kinase activity protein binding ATP binding transcription factor binding kinase activity TBP-class protein binding sequence-specific DNA binding protein heterodimerization activity ubiquitin conjugating enzyme activity lysine-acetylated histone binding acetyl-CoA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription regulatory region DNA binding transferase activity chromatin binding protein complex scaffold activity transferase activity, transferring acyl groups H4 histone acetyltransferase activity histone acetyltransferase activity (H3-K14 specific)	TAF1 (S. cerevisiae) taf-1 (C. elegans) Taf1 (D. melanogaster)