PDGFRB - PCSK9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
PCSK9	ENSG00000169174	No diseases in record	No drugs in record	serine-type endopeptidase activity protein binding sodium channel inhibitor activity low-density lipoprotein particle binding receptor inhibitor activity apolipoprotein binding very-low-density lipoprotein particle binding apolipoprotein receptor binding protein self-association low-density lipoprotein particle receptor binding very-low-density lipoprotein particle receptor binding	PRB1 (S. cerevisiae) RRT12 (S. cerevisiae) YSP3 (S. cerevisiae)