XRN1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XRN1	ENSG00000114127	No diseases in record	No drugs in record	DNA binding exonuclease activity protein binding mRNA binding chromatin binding 5'-3' exoribonuclease activity RNA binding hydrolase activity nuclease activity nucleic acid binding 5'-3' exonuclease activity	XRN1 (S. cerevisiae) xrn-1 (C. elegans) pcm (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)