KDR - RUNX1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)
RUNX1	ENSG00000159216	AML pre B-ALL T-ALL	No drugs in record	regulatory region DNA binding RNA polymerase II regulatory region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protein binding ATP binding	rnt-1 (C. elegans) run (D. melanogaster) lz (D. melanogaster)