INO80 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
INO80	ENSG00000128908	No diseases in record	No drugs in record	DNA binding DNA helicase activity actin binding protein binding ATP binding ATPase activity alpha-tubulin binding helicase activity hydrolase activity nucleotide binding ATP-dependent 3'-5' DNA helicase activity regulatory region DNA binding	INO80 (S. cerevisiae) Ino80 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)