BRAF - TCF4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
TCF4	ENSG00000196628	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, TFIIB-class binding TFIIB-class transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding identical protein binding protein homodimerization activity bHLH transcription factor binding protein heterodimerization activity E-box binding	hlh-2 (C. elegans)