THRB - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
THRB	ENSG00000151090	No diseases in record	DEXTROTHYROXINE LEVOTHYROXINE LIOTHYRONINE	DNA binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription corepressor activity thyroid hormone receptor activity protein binding zinc ion binding enzyme binding chromatin DNA binding sequence-specific DNA binding thyroid hormone binding	EcR (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)