BRAF - RUVBL2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
RUVBL2	ENSG00000183207	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding DNA helicase activity ATP-dependent DNA helicase activity protein binding ATP binding chromatin DNA binding identical protein binding ATP-dependent 5'-3' DNA helicase activity unfolded protein binding ATPase activity	RVB2 (S. cerevisiae) rept (D. melanogaster)