BRAF - BCR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
BCR	ENSG00000186716	CML ALL AML	PONATINIB	protein serine/threonine kinase activity protein tyrosine kinase activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding ATP binding kinase activity enzyme binding	BEM2 (S. cerevisiae)