PPP3CA - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPP3CA	ENSG00000138814	No diseases in record	No drugs in record	protein serine/threonine phosphatase activity calcium ion binding protein binding calmodulin binding drug binding enzyme binding calmodulin-dependent protein phosphatase activity protein heterodimerization activity protein dimerization activity	CMP2 (S. cerevisiae) CNA1 (S. cerevisiae) tax-6 (C. elegans) CanA1 (D. melanogaster) Pp2B-14D (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)