HDAC7 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC7	ENSG00000061273	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN	chromatin binding transcription corepressor activity protein kinase C binding protein binding SUMO transferase activity protein kinase binding NAD-dependent histone deacetylase activity (H3-K14 specific) activating transcription factor binding metal ion binding repressing transcription factor binding 14-3-3 protein binding	HDA1 (S. cerevisiae) hda-4 (C. elegans) HDAC4 (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)