TDP1 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TDP1	ENSG00000042088	No diseases in record	No drugs in record	double-stranded DNA binding single-stranded DNA binding exonuclease activity protein binding 3'-tyrosyl-DNA phosphodiesterase activity hydrolase activity nuclease activity 5'-tyrosyl-DNA phosphodiesterase activity phosphoric diester hydrolase activity	TDP1 (S. cerevisiae) gkt (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)