UBR5 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
UBR5	ENSG00000104517	mantle cell lymphoma gastric colorectal	No drugs in record	RNA binding ubiquitin-protein transferase activity protein binding zinc ion binding ubiquitin-ubiquitin ligase activity ubiquitin binding	TOM1 (S. cerevisiae) ubr-5 (C. elegans) hyd (D. melanogaster)
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)