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Slorth
BRAF - JAK1
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
BRAF
ENSG00000157764
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)
JAK1
ENSG00000162434
ALL
RUXOLITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
protein binding
ATP binding
protein phosphatase binding
ubiquitin protein ligase binding
CCR5 chemokine receptor binding
metal ion binding
hop (D. melanogaster)