NCOA2 - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NCOA2	ENSG00000140396	AML chondrosarcoma rhabdomyosarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding transcription factor binding ligand-dependent nuclear receptor binding ligand-dependent nuclear receptor transcription coactivator activity thyroid hormone receptor coactivator activity nuclear hormone receptor binding protein dimerization activity	No GO terms in record
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)