THRB - KIT

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
THRB ENSG00000151090

No diseases in record

DEXTROTHYROXINE
LEVOTHYROXINE
LIOTHYRONINE
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription corepressor activity
thyroid hormone receptor activity
protein binding
zinc ion binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
thyroid hormone binding
EcR (D. melanogaster)
KIT ENSG00000157404 GIST
AML
TGCT
mastocytosis
mucosal melanoma
epithelioma
CABOZANTINIB
DASATINIB
IMATINIB
LENVATINIB
PAZOPANIB
PONATINIB
REGORAFENIB
SORAFENIB
SUNITINIB
protease binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
stem cell factor receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
cytokine binding
protein homodimerization activity
metal ion binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Pvr (D. melanogaster)