KIT - CDK5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)
CDK5	ENSG00000164885	No diseases in record	No drugs in record	p53 binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ErbB-2 class receptor binding protein binding ATP binding cytoskeletal protein binding kinase activity protein kinase binding acetylcholine receptor activator activity ErbB-3 class receptor binding ephrin receptor binding tau-protein kinase activity	CDC28 (S. cerevisiae) cdk-5 (C. elegans) Cdk5 (D. melanogaster)