GNAO1 - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GNAO1	ENSG00000087258	No diseases in record	No drugs in record	GTPase activity signal transducer activity GTP binding G-protein beta/gamma-subunit complex binding G-protein coupled serotonin receptor binding mu-type opioid receptor binding GTPase activating protein binding metal ion binding corticotropin-releasing hormone receptor 1 binding	GPA2 (S. cerevisiae) Galphao (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)