KIT - MCM7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)
MCM7	ENSG00000166508	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding DNA binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity chromatin binding DNA replication origin binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity single-stranded DNA-dependent ATPase activity hydrolase activity nucleotide binding ATP-dependent four-way junction helicase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM7 (S. cerevisiae) Mcm7 (D. melanogaster)