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EZH2 - KIT
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
EZH2
ENSG00000106462
DLBCL
No drugs in record
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
DNA binding
chromatin binding
protein binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
chromatin DNA binding
histone methyltransferase activity
ribonucleoprotein complex binding
histone methyltransferase activity (H3-K27 specific)
primary miRNA binding
promoter-specific chromatin binding
SET2 (S. cerevisiae)
lin-59 (C. elegans)
E(z) (D. melanogaster)
KIT
ENSG00000157404
GIST
AML
TGCT
mastocytosis
mucosal melanoma
epithelioma
CABOZANTINIB
DASATINIB
IMATINIB
LENVATINIB
PAZOPANIB
PONATINIB
REGORAFENIB
SORAFENIB
SUNITINIB
protease binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
stem cell factor receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
cytokine binding
protein homodimerization activity
metal ion binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
Pvr (D. melanogaster)