HSP90AB1 - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HSP90AB1	ENSG00000096384	NHL	No drugs in record	glycoprotein binding UTP binding CTP binding double-stranded RNA binding protein binding ATP binding GTP binding drug binding sulfonylurea receptor binding protein kinase regulator activity kinase binding protein kinase binding MHC class II protein complex binding nitric-oxide synthase regulator activity TPR domain binding heat shock protein binding dATP binding histone deacetylase binding ion channel binding protein dimerization activity unfolded protein binding cadherin binding involved in cell-cell adhesion histone methyltransferase binding	HSC82 (S. cerevisiae) HSP82 (S. cerevisiae) daf-21 (C. elegans) Hsp83 (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)